Preoperative aspirin continuation versus replacement therapy with low molecular weight heparin before coronary surgery: effects on postoperative bleeding risk.
نویسندگان
چکیده
Background/Introduction Management of preoperative antiplatelet therapy in coronary surgery is still variable among surgeons. Guidelines collide with prejudices: replacement of aspirin with low molecular weight heparin (LMWH) is still performed in many Centers due to a presumed minor risk of intraoperative bleeding, even though supporting evidences are weak and detrimental effects are well-described.
منابع مشابه
The Effect of Preoperative Aspirin and/or Heparin Therapy on Coagulation and Postoperative Blood Loss after Coronary Artery Bypass Surgery.
OBJECTIVE To assess the effects of preoperative aspirin and/or intravenous heparin therapy on perioperative coagulation tests and postoperative blood loss for 24-hour after coronary artery bypass surgery. METHODS Multiple conventional coagulation tests, activated clotting time, thrombelastograph, skin bleeding time and platelet aggregation were performed before induction of anaesthesia, follo...
متن کاملEffects of Preoperative Enoxaparin on Bleeding after Coronary Artery Bypass Surgery.
BACKGROUND Low molecular weight heparins are replacing unfractionated heparin in practice prior to cardiac surgery. This study examines postoperative (post-op) bleeding indicators in patients who received enoxaparin and underwent elective isolated first time coronary artery bypass graft. METHODS A total of 125 consecutive patients who underwent this procedure between 2009 and 2011 at one tert...
متن کاملPerioperative handling of patients on antiplatelet therapy with need for surgery.
The widespread use of metal stents and drug-eluting stents has shown the extent to which patients with unstable coronary perfusion depend on antiplatelet drugs, and how their risk of late thrombosis depends on the long-term use of agents such as clopidogrel. It has also been shown that the risk of surgical bleeding, if antiplatelet drugs are continued, is lower than that of coronary thrombosis ...
متن کاملPreoperative aspirin therapy is associated with improved postoperative outcomes in patients undergoing coronary artery bypass grafting.
BACKGROUND Aspirin is beneficial in the setting of atherosclerotic cardiovascular disease. There are limited data evaluating preoperative aspirin administration preceding coronary artery bypass grafting and associated postoperative outcomes. METHODS AND RESULTS Using prospectively collected data from 1636 consecutive patients undergoing first-time isolated coronary artery bypass surgery at ou...
متن کاملIncidence of venous thromboembolism and hemorrhage related safety studies of preoperative anticoagulation therapy in hip fracture patients undergoing surgical treatment: a case–control study
BACKGROUND Venous thromboembolism is a common postoperative complication following orthopedic surgeries, with morbid and potentially fatal consequences. Perioperative low-molecular-weight heparin (LMWH) therapy can reduce the incidence of venous thromboembolism, but may also increase the risk of bleeding complications. Current literature reflects the need to balance the improved efficacy of ear...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of cardiothoracic surgery
دوره 10 Suppl 1 شماره
صفحات -
تاریخ انتشار 2015